An introduction to computational biochemistry

C. Stan Tsai047140120X, 9780471401209

This comprehensive text offers a solid introduction to the biochemical principles and skills required for any researcher applying computational tools to practical problems in biochemistry. Each chapter includes an introduction to the topic, a review of the biological concepts involved, a discussion of the programming and applications used, key references, and problem sets and answers. Providing detailed coverage of biochemical structures, enzyme reactions, metabolic simulation, genomic and proteomic analyses, and molecular modeling, this is the perfect resource for students and researchers in biochemistry, bioinformatics, bioengineering and computational science.

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Table of contents :
Cover……Page 1
Preface……Page 9
Introduction……Page 11
Biochemical Data: Analysis and Management……Page 21
Biochemical Explorations: Internet Resources……Page 51
Molecular Graphics: Visualizations of Biomolecules……Page 63
Biochemical Compounds: Structure and Analysis……Page 82
Dynamic Biochemistry: Biomolecular Interactions……Page 115
Dynamic Biochemistry: Enzyme Kinetics……Page 130
Dynamic Biochemistry: Metabolic Simulation……Page 154
Genomics: Nucleotide Sequences and Recombinant DNA……Page 171
Genomics: Gene Identification……Page 189
Proteomics: Protein Sequence Analysis……Page 215
Proteomics: Prediction of Protein Structure……Page 238
Phylogenetic Analysis……Page 274
Molecular Modeling: Molecular Mechanics……Page 290
Molecular Modeling: Protein Modeling……Page 320
Appendix……Page 347
Index……Page 360