Risk of arrhythmia and sudden death

Marek Malik9780727915818, 0727915819

(BMJ Books) St. George’s Hospital Medical School, London, UK. Four sections cover general principles of risk stratification, individual investigation techniques aimed at patients at high risk, application of risk stratification technologies and tests, and summarizes clinical trials utilizing these techniques.

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Table of contents :
Cover……Page 1
Contents……Page 6
Contributors……Page 10
Preface……Page 14
Abbreviations……Page 16
Part I: Problem and methodology……Page 18
1 Clinical goals of risk stratification……Page 20
2 Definition of arrhythmic risk……Page 27
3 Statistical methods for risk-stratification studies……Page 36
4 Step-wise risk-stratification strategies……Page 46
5 Risk-stratification studies for prospective trial design……Page 54
Part II: Techniques of risk assessment……Page 64
6 Basic clinical assessment……Page 66
7 Left ventricular ejection fraction and wall motion score……Page 74
8 Risk assessment: the 12-lead electrocardiogram……Page 82
9 Electrophysiological study for risk stratification of cardiac patients……Page 115
10 QT dispersion……Page 134
11 Electrocardiographic assessment of myocardial ischaemia……Page 152
12 Exercise electrocardiography for the assessment of arrhythmias……Page 161
13 Analysis of monophasic action potentials……Page 172
14 Ventricular signal averaged electrocardiography……Page 184
15 Signal averaged P wave……Page 197
16 Non-invasive investigation of Wedensky modulation……Page 204
17 Ambulatory electrocardiography: use in arrhythmia risk assessment……Page 211
18 Event loop recorders and implantable monitors……Page 219
19 Basic autonomic tests……Page 226
20 Heart rate assessment and monitoring……Page 230
21 Heart rate variability……Page 238
22 Baroreflex sensitivity……Page 251
23 Heart rate turbulence……Page 259
24 T wave dynamicity……Page 266
25 Repolarisation alternans……Page 273
26 Social and psychosocial influences on sudden cardiac death……Page 283
Part III: Clinical studies of risk assessment……Page 302
27 Risk stratification after myocardial infarction……Page 304
28 Ventricular arrhythmias in chronic heart failure……Page 314
29 Ventricular arrhythmias in hypertrophic cardiomyopathy……Page 326
30 Ventricular arrhythmias in apparently healthy athletes……Page 333
31 Paroxysmal atrial fibrillation……Page 342
32 Persistent atrial fibrillation……Page 353
33 Permanent atrial fibrillation……Page 365
34 Arrhythmias associated with the long QT syndrome……Page 370
35 Arrhythmia associated with other cardiac diseases……Page 377
36 Arrhythmias associated with non-cardiac disease……Page 382
Part IV: Antiarrhythmic trials……Page 394
37 Antiarrhythmic device trials……Page 396
38 Recent antiarrhythmic drug trials……Page 406
Index……Page 412