The Alkaloids: Chemistry and Biology, Vol. 64

Geoffrey A. Cordell (Ed.)978-0-12-373911-7

Once again, this volume of “The Alkaloids: Chemistry and Biology” is comprised of four quite different chapters, from three different continents, on mechanisms of cytotoxic action, the calystegines, strychnine synthesis, and substituted quinoline alkaloids. This diversity reflects the need to see alkaloids as a class of natural product having tremendous biological potential and of continued broad scientific interest.

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Table of contents :
Content:
The Alkaloids Chemistry and Biology
Page iii

Copyright Page
Page iv

Contributors
Page vii

Preface
Page ix

Chapter 1 Molecular Modes of Action of Cytotoxic Alkaloids: From DNA Intercalation, Spindle Poisoning, Topoisomerase Inhibition to Apoptosis and Multiple Drug Resistance Review Article
Pages 1-47
Michael Wink

Chapter 2 Calystegines Review Article
Pages 49-102
Stefan Biastoff, Birgit Dräger

Chapter 3 Recent Studies on the Synthesis of Strychnine Review Article
Pages 103-138
Masakatsu Shibasaki, Takashi Ohshima

Chapter 4 Alkyl, Aryl, Alkylarylquinoline, and Related Alkaloids Review Article
Pages 139-214
Maria Fátima das Graças Fernandes da Silva, Márcio Santos Soares, João Batista Fernandes, Paulo Cezar Vieria

Cumulative Index of Titles
Pages 215-222

Subject Index
Pages 223-237