Ergot. The Genus Claviceps [ergotamine, LSD]

Vladimir Kren, Ladislav Cvak9789057023750, 905702375X

The sixth volume in the series Medicinal and Aromatic Plants – Industrial Profiles is written by experts actively working in ergot research. Ergot (Claviceps purpurrea) is best known as a disease of rye and grasses. It is probably the most widely cultivated fungus and it has become an important field crop. Ergot alkaloids, which are extensively used in medicine, are the main reason for its importance. The book begins with the history of ergot research which is comparable to that of the discovery of penicillin. Review articles on Claviceps taxonomy, genetics, biogenesis and pharmacology are based on recent achievements in molecular biology – some of them published here for the first time. The chapters on ergot cultivation, physiology and biotechnology are written by distinguished experts in industry. Sections dealing with the chemistry of ergot alkaloids and biotransformation are comprehensive and serve as good reference material. Unique information on world producers and

---

Table of contents :
Front cover
……Page 1
Table of contents
……Page 4
Preface to the series
……Page 6
Preface
……Page 8
Names of ergot
……Page 10
1 – The history of ergot
……Page 14
2 – Biology and Life Strategy of the Ergot Fungi
……Page 38
3 – The Taxonomy and Phylogeny of Claviceps
……Page 70
4 – Genetics of Claviceps purpurea
……Page 92
5 – Biosynthesis of Ergot Alkaloids
……Page 108
6 – Physiological Regulation of Ergot Alkaloid Production
……Page 178
7 – Ergot Alkaloids and Other Metabolites of the, Genus Claviceps
……Page 186
8 – Chemical Modifications of Ergot Alkaloids
……Page 214
9 – Biotransformations of Ergot Alkaloids
……Page 242
10 – Analytical Chemistry of Ergot Alkaloids
……Page 280
11 – Parasitic Production of Ergot Alkaloids
……Page 316
12 – Saprophytic Cultivation of Claviceps
……Page 334
13 – Industrial Production of Ergot Alkaloids
……Page 386
14 – Ergot Alkaloids and their Derivatives as Ligands for Serotoninergic, Dopaminergic, and Adrenergic Receptors
……Page 424
15 – Antimicrobial and Antitumor Effects of Ergot Alkaloids and their Derivatives
……Page 454
16 – Role of Ergot Alkaloids in the Immune System
……Page 464
17 – Toxicology of Ergot Alkaloids in Agriculture
……Page 482
18 – Producers of Ergot Alkaloids out of Clav
iceps Genus……Page 492
Index
……Page 514