Molecular Genetics of Cancer

J.K. Cowell0-203-45038-8, 1-85996-169-X

Since the first volume was published, there has been significant success in isolating genes responsible for particular cancers as well as a major improvement in our understanding of the molecular events leading to tumors. This book explores possible genetic treatments that can suppress cancer cells that have formed tumors and it presents the details of the isolation and characterization of new human cancer genes that have recently been identified. Molecular Genetics of Cancer, 2E is an essential book for anyone involved in cancer research and the search for a cure.

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Table of contents :
Book Cover……Page 1
Half-Title……Page 2
Title……Page 5
Copyright……Page 6
Contents……Page 7
Contributors……Page 9
Abbreviations……Page 12
Preface to the Second Edition……Page 17
Preface to the First Edition……Page 19
1 Basic Principles in Cancer Genetics……Page 21
2 Defining Genetic Changes Associated with Cutaneous Malignant Melanoma……Page 60
3 The Genetics of Breast and Ovarian Cancer……Page 84
4 Genetics of Von Hippel Lindau Disease……Page 120
5 Genetics of NF1 and NF2……Page 138
6 Genetics of Gastric Cancer……Page 163
7 Multiple Endocrine Neoplasia Type 1……Page 206
8 Multiple Endocrine Neoplasia Type 2……Page 238
9 TP53 in Cancer Origin and Treatment……Page 268
10 Colorectal Cancer……Page 316
11 Genetics of Prostate Cancer……Page 343
12 Tuberous Sclerosis Complex……Page 370
13 Retinoblastoma: Patients, Tumors, Gene and Protein Contribute to the Understanding of Cancer……Page 395
14 Genetics of Wilms Tumor……Page 418
15 Genetics of Neuroblastoma……Page 440
16 Genetics of Brain Tumors……Page 476
17 Molecular Genetics of Lung Cancer……Page 505
18 Genetics of Liver Cancer……Page 539
19 The Genetics of Bladder Cancer……Page 564
20 Genetics of Rhabdomyosarcoma……Page 598
21 Role of Telomeres and Telomerase in Aging and Cancer……Page 625
Index……Page 657