Peter J. Schoenmakers (Eds.)0444416161, 9780444416162
In this two-part monograph, the author describes modern methods for the rapid column liquid chromatography of high- and medium-molecular-weight compounds of biological origin, i.e. proteins, peptides, enzymes, nucleic acids, poly- and oligonucleotides, poly- and oligosaccharides, complex biopolymers and biooligomers such as viruses, bacteriophages, ribosomes and glycoconjugates, as well as some other compounds such as immunomodulators. The material is contained in two parts: Part A dealing with general chromatographic theory, principles, materials and techniques; and Part B dealing with the separation of individual compound classes and containing a register of chromatographed substances and a full-title bibliography. Not only is this a specialized, detailed treatise on chromatographic techniques, it also gives a broad, balanced review of rapid separation of all known important biopolymers and biooligomers, both simple and complex, and also of some synthetically prepared and pharmaceutically important biooligomers. In addition, it provides an introduction to the application of HPLC to the study of the structure of these substances. |
Table of contents :
Content:
Edited by
Page III Copyright page
Page IV Journal of Chromatography Library
Pages IX-XI Preface
Pages XIII-XIV
Peter Schoenmakers Acknowledgements
Page XV Chapter 1 Introduction
Pages 1-19 Chapter 2 Selection of Methods
Pages 20-36 Chapter 3 Parameters Affecting Selectivity
Pages 37-115 Chapter 4 Optimization Criteria
Pages 116-169 Chapter 5 Optimization Procedures
Pages 170-252 Chapter 6 Programmed Analysis
Pages 253-295 Chapter 7 System Optimization
Pages 296-319 Symbols and Abbreviations
Pages 321-327 Author Index
Pages 329-332 Subject Index
Pages 333-345 |
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