Molecular Diagnosis of Cancer

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Edition: 1

Series: Methods in Molecular Medicine

ISBN: 9780896033412, 0896033414

Size: 13 MB (13483106 bytes)

Pages: 236/0

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Finbarr Cotter9780896033412, 0896033414

Leading clinicians and expert researchers bring together under one cover a comprehensive guide to the newest and most essential molecular techniques-particularly PCR-for diagnosing and monitoring hematological and solid tumors. These distinguished practitioners demonstrate step-by-step the use of PCR, FISH, CGH, Southern analysis, sequencing, and SSCP to assess cancer markers, to detect minimal disease and apoptosis, and to uncover particular translocations, mutations, and deletions. Their readily reproducible results offer physicians and scientists a promising entré into the powerful possibilities of using these techniques to improve the diagnosis, prognosis, and management of cancer.

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