Dynamics of the Vascular System

John K-J Li9789810249076, 981-02-4907-1

Recent advances in vascular biology and vascular engineering have led to the understanding and integration of the two fields. A feature that is fundamental to both is the dynamic aspects of the vascular system. Although the basic principles governing blood flow and the circulatory function are known, new approaches to examining the interaction of different parts of the vascular system have emerged. These include measurement techniques and quantitative methods with greater use of modern technology and computer modeling. An obvious need therefore exists for a book that deals specifically with the dynamics of the vascular system.
This book begins with the historical discoveries of the features of the vascular system and its importance in the overall circulatory function. Modern aspects of vascular biology in terms of structure and function are then described, followed by the introduction of physical principles and basic fluid mechanics for quantitative analysis. The hemodynamics of large arteries, the optimal structure of vascular branching and the pulsatile energy transmission and modeling aspects are elaborated. These are extended to analyze the function of the venous system and the microcirculation. Finally, the integrated vascular system and its response and adaptation to diseased conditions, such as aging, stenosis, hypertension, myocardial ischemia, atheroslerosis and stroke are explained. The overall emphasis is on the dynamic nature of the vascular system.

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Table of contents :
Cover……Page 1
Author Biography……Page 6
Preface……Page 8
Contents……Page 10
1 . Historical Backgrounds and Book Contents……Page 14
2 . Vascular Biology, Structure and Function……Page 27
3 . Physical Concepts and Basic Fluid Mechanics……Page 54
4 . Hemodynamics of Large Arteries……Page 89
5 . Vascular Branching……Page 155
6 . The Venous System……Page 185
7 . The Microcirculation……Page 205
8 . Hemodynamic Measurements and Dynamics of the Assisted Circulation……Page 227
Bibliography……Page 258
Index……Page 266