Medicinal Natural Products: A Biosynthetic Approach

Paul M. Dewick0471496405, 9780471496410, 9780471496403, 9780470846278, 0471496413

Medicinal Natural Products, Second Edition is a comprehensive guide providing information on all classes of natural products in medicine. It builds upon fundamental chemical principles and demonstrates a unique integration of plant, microbial and animal natural products in one volume. The text guides the reader through a wealth of diverse natural metabolites used in medicine with sources, production methods, use as drugs and modes of action all extensively covered. Taking a chemistry based approach it combines traditional pharmacognosy with medicinal chemistry. The structure is user-friendly and includes the acclaimed grey boxes on groups of products and detailed mechanistic explanations. Adopts a novel biosynthetic theme rather than a traditional descriptive approach Includes extensive further reading at the end of the chapter Thoroughly revised and updated to incorporate comprehensive coverage of plant, microbial and animal products Includes the latest developments in the field New material on genetic manipulation of biosynthetic pathways and non-mevalonate pathway to terpanoids User-friendly format including extensive use of chemical schemes with annotated mechanistic explanations