The GABA Receptors

S. J. Enna, S. J. Enna, Hanns Möhler9781588298133, 1588298132

& Quot;The Gaba Receptors, Third Edition,” presents a critical appraisal of our current understanding of the molecular, behavioral, biochemical, clinical, and pharmacological properties of GABA receptors. Emphasis is placed on exploring cutting-edge findings on the structural properties of receptor sites, mechanisms of receptor expression, chemical agents that differentiate receptor subtypes, and phenotypes displayed by GABA receptor null mice. Chapters in this updated and expanded edition examine such topics as GABA receptor subtypes, trafficking postsynaptic GABA receptors, GABA receptor. Read more… Content: Front Matter; The GABA Receptors; Functional Relevance of GABAA-Receptor Subtypes; Trafficking of Postsynaptic GABAA Receptors by Receptor-Associated Proteins; Subunit Composition and Structure of GABAA-Receptor Subtypes; Differential Activation of GABAA-Receptor Subtypes; GABAA-Receptor Mutations Associated With Idiopathic Generalized Epilepsies and Febrile Seizures; Abuse and Dependence Liability of GABAA-Receptor Modulators; Mechanisms of GABAA and GABAB Receptor Gene Regulation and Cell Surface Expression; Chemistry of GABAB Modulators. Abstract: Presents a critical appraisal of our understanding of the molecular, behavioral, biochemical, clinical, and pharmacological properties of GABA receptors. This title examines such topics as GABA receptor subypes, trafficking postsynaptic GABA receptors, GABA receptor mutations associated with idiopathic generalized epilepsies and febrile seizures. Read more…