Analgesia

Christoph Stein, Christoph Stein9783540338222, 3-540-33822-5

This volume attempts to summarize the current state of knowledge on mechanisms underlying the various effects of analgesics, their side effect profiles, and their indications and contraindications in clinical use. It also gives insights into current efforts to discover novel mechanisms underlying the generation of different types of pain and the resulting development of new modulating compounds.

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Table of contents :
Cover……Page 1
01 – Front Matter……Page 2
011 – Front Matter……Page 9
012 – Peripheral and Central Mechanisms of Pain Generation……Page 10
021 – Front Matter……Page 36
022 – Opioids……Page 37
023 – Antipyretic Analgesics – Nonsteroidal Antiinflammatory Drugs, Selective COX-2 Inhibitors, Paracetamol and Pyrazolinones……Page 70
024 – Local Anesthetics……Page 99
025 – Serotonin Receptor Ligands – Treatments of Acute Migraine and Cluster Headache……Page 132
026 – Anti-convulsants and Anti-depressant……Page 147
031 – Front Matter……Page 180
032 – Neuropeptide and Kinin Antagonists……Page 181
033 – Glutamate Receptor Ligands……Page 217
034 – Adrenergic and Cholinergic Compounds……Page 250
035 – Cannabinoids and Pain……Page 264
041 – Front Matter……Page 306
042 – Adenosine and ATP Receptors……Page 307
043 – Ion Channels in Analgesia Research……Page 327
044 – Protein Kinases as Potential Targets for the Treatment of Pathological Pain……Page 357
051 – Front Matter……Page 388
052 – Placebo and Endogenous Mechanisms of Analgesia……Page 389
053 – Limitations of Pharmacotherapy – Behavioral Approaches to Chronic Pain……Page 410
06 – Back Matter……Page 423