Drug Targeting

Molema G., Meijer D.K.F.

How are medicines transported intact through the body to their specific target sites without triggering side effects? The answer is “Drug Targeting”. This thoroughly application-oriented book gives comprehensive answers to this and many other questions that confront scientists daily in chemical, pharmaceutical and medical research. Aconcise overview of the most important basic theories, modern forms of therapy and molecular biological tools, it represents a comprehensible introduction to the topic. The book then goes on to deal with strategies for target applications, divided according totarget site, for example brain, lungs, liver, blood vessels and tumor cells. The third part is devoted to special, modern techniques, from phage display methods, via the use of tissue slices right up to pharmacokinetic modeling. Throughout, the focus remains on thepractical aspect and successful application of the method in question, although a glance at what the future holds is also included. A volume that every pharmaceutically oriented research group should own.