Mechanosensitive Ion Channels, Part B

Owen P. Hamill (Eds.)978-0-12-153359-5

Current Topics in Membranes provides a systematic, comprehensive, and rigorous approach to specific topics relevant to the study of cellular membranes. Each volume is a guest edited compendium of membrane biology. This series has been a mainstay for practicing scientists and students interested in this critical field of biology. Articles covered in the volume include ENaC Proteins in Vascular Smooth Muscle Mechanotransduction; Regulation of the Mechano-Gated K2P Channel TREK-1 by Membrane Phospholipids; MechanoTRPs and TRPA1; TRPC; The Cytoskeletal Connection to Ion Channels as a Potential Mechanosensory Mechanism. Lessons From Polycystin-2 (TRPP2); Lipid Stress at Play: Mechanosensitivity of Voltage-Gated Channels; Hair Cell Mechanotransduction: The Dynamic Interplay between Structure and Function; Pharmacology of Hair Cell MS Channels; Hair Cell Mechanotransduction; Models of Hair Cell Mechanotrasduction; Touch; Mechanosensitive Ion Channels in Dystrophic Muscle; Mechanotransduction in Endothelial Cells;MS Channels in Tumor Cell Migration; Mechanosensitive Channels in Regulating Smooth Muscle Contraction in the GI; Mechanosensitive Ion Channels in Blood-Pressure-Sensing Baroreceptor Neurons.

---

Table of contents :
Content:
Mechanosensitive Ion Channels of Spiders: Mechanical Coupling, Electrophysiology, and Synaptic Modulation Review Article
Pages 1-20
Andrew S. French, Päivi H. Torkkeli

Ion Channels for Mechanotransduction in the Crayfish Stretch Receptor Review Article
Pages 21-48
Bo Rydqvist

Mechanosensitive Ion Channels in Caenorhabditis elegans Review Article
Pages 49-79
Dafne Bazopoulou, Nektarios Tavernarakis

Properties and Mechanism of the Mechanosensitive Ion Channel Inhibitor GsMTx4, a Therapeutic Peptide Derived from Tarantula Venom Review Article
Pages 81-109
Philip A. Gottlieb, Thomas M. Suchyna, Frederick Sachs

Mechanosensitive Channels in Neurite Outgrowth Review Article
Pages 111-125
Mario Pellegrino, Monica Pellegrini

ENaC Proteins in Vascular Smooth Muscle Mechanotransduction Review Article
Pages 127-153
Heather A. Drummond

Regulation of the Mechano‐Gated K2P Channel TREK‐1 by Membrane Phospholipids Review Article
Pages 155-170
Jean Chemin, Amanda Jane Patel, Patrick Delmas, Frederick Sachs, Michel Lazdunski, Eric Honore

MechanoTRPs and TRPA1 Review Article
Pages 171-189
Andrew J. Castiglioni, Jaime García‐Añoveros

TRPCs as MS Channels Review Article
Pages 191-231
Owen P. Hamill, Rosario Maroto

The Cytoskeletal Connection to Ion Channels as a Potential Mechanosensory Mechanism: Lessons from Polycystin‐2 (TRPP2) Review Article
Pages 233-296
Horacio F. Cantiello, Nicolás Montalbetti, Qiang Li, Xing‐Zhen Chen

Lipid Stress at Play: Mechanosensitivity of Voltage‐Gated Channels Review Article
Pages 297-338
Catherine E. Morris, Peter F. Juranka

Hair Cell Mechanotransduction: The Dynamic Interplay Between Structure and Function Review Article
Pages 339-374
Anthony J. Ricci, Bechara Kachar

Insights into the Pore of the Hair Cell Transducer Channel from Experiments with Permeant Blockers Review Article
Pages 375-398
Sietse M. van Netten, Corné J. Kros

Models of Hair Cell Mechanotransduction Review Article
Pages 399-424
Susanne Bechstedt, Jonathon Howard

Touch Review Article
Pages 425-465
Liam J. Drew, Francois Rugiero, John N. Wood

Mechanosensitive Ion Channels in Dystrophic Muscle Review Article
Pages 467-484
Jeffry B. Lansman

MscCa Regulation of Tumor Cell Migration and Metastasis Review Article
Pages 485-509
Rosario Maroto, Owen P. Hamill

Stretch‐Activated Conductances in Smooth Muscles Review Article
Pages 511-540
Kenton M. Sanders, Sang Don Koh

Mechanosensitive Ion Channels in Blood Pressure‐Sensing Baroreceptor Neurons Review Article
Pages 541-567
Mark W. Chapleau, Yongjun Lu, Francois M. Abboud

Series Editors
Page II

Contents
Pages V-XI

Contributors to Volume 59
Pages XIII-XVI

Foreword: Mechanosensitive Ion Channels, Part B
Pages XVII-XVIII
Owen P. Hamill

Index
Pages 569-588

Previous Volumes in Series
Pages XIX-XXI