Molecular Biology

Robert F. Weaver9780072345179, 0072345179

Molecular Biology, 2/e emphasizes the experimental data and results that support the concepts of molecular biology: DNA transcription, translation, replication, and repair. Experimental methods are extensively covered. The text presumes a prior course in general genetics.

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Table of contents :
Front Matter……Page 2
Preface……Page 3
Guide to Experimental Techniques in Molecular Biology……Page 5
1. A Brief History……Page 7
2. The Molecular Nature of Genes……Page 22
3. An Introduction to Gene Function……Page 44
4. Molecular Cloning Methods……Page 65
5. Molecular Tools for Studying Genes and Gene Activity……Page 97
6. The Transcription Apparatus of Prokaryotes……Page 139
7. Operons: Fine Control of Prokaryotic Transcription……Page 181
8. Major Shifts in Prokaryotic Transcription……Page 211
9. DNA-Protein Interactions in Prokaryotes……Page 237
10. Eukaryotic RNA Polymerases and Their Promoters……Page 267
11. General Transcription Factors in Eukaryotes……Page 303
12. Transcription Activators in Eukaryotes……Page 348
13. Chromatin Structure and Its Effects on Transcription……Page 386
14. Splicing……Page 424
15. Capping and Polyadenylation……Page 468
16. Other Events……Page 503
17. Initiation……Page 534
18. Elongation and Termination……Page 573
19. Ribosomes and Transfer RNA……Page 612
20. DNA Replication I: Basic Mechanism and Enzymology……Page 648
21. DNA Replication II: Detailed Mechanism……Page 690
22. Homologous Recombination……Page 723
23. Site-Specific Recombination and Transposition……Page 753
24. Genomics……Page 790
Glossary……Page 825
Index……Page 848