Molecularly Imprinted Polymers: Man-made Mimics of Antibodies and their Applications in Analytical Chemistry

Börje Sellergren (Eds.)0444828370, 9780444828378

This book is divided into 5 sections starting with an historic perspective and fundamental aspects on the synthesis and recognition by imprinted polymers. The second section contains 8 up-to-date overview chapters on current approaches to molecular and ion imprinting. This is followed by two chapters on new material morphologies and in the last two sections various analytical applications of imprinted polymers are given, with the last four chapters devoted to the promising field of imprinted polymers in chemical sensors.The authors of this volume have widely different backgrounds; mainly polymer chemistry, organic chemistry, biochemistry and analytical chemistry, which means that this book has an interdisciplinary character and should appeal to a broad audience.

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Table of contents :
Content:
Preface
Pages xvii-xviii
Börje Sellergren

List of contributors
Pages xix-xxi

List of abbreviations
Pages xxii-xxiv

Chapter 1 A historical perspective of the development of molecular imprinting Original Research Article
Pages 1-19
Håkan S. Andersson, Ian A. Nicholls

Chapter 2 Fundamental aspects on the synthesis and characterisation of imprinted network polymers Original Research Article
Pages 21-57
Börje Sellergren, Andrew J. Hall

Chapter 3 Thermodynamic principles underlying molecularly imprinted polymer formulation and ligand recognition Original Research Article
Pages 59-70
Ian A. Nicholls, Håkan S. Andersson

Chapter 4 Molecular imprinting with covalent or stoichiometric non-covalent interactions Original Research Article
Pages 71-111
Günter Wulff, Andrea Biffis

Chapter 5 The non-covalent approach to molecular imprinting Original Research Article
Pages 113-184
Börje Sellergren

Chapter 6 Metal-ion coordination in designing molecularly imprinted polymeric receptors Original Research Article
Pages 185-201
Pradeep K. Dhal

Chapter 7 Covalent imprinting using sacrificial spacers Original Research Article
Pages 203-212
Michael J. Whitcombe, Evgeny N. Vulfson

Chapter 8 Molecular imprinting approaches using inorganic matrices Original Research Article
Pages 213-244
Darryl Y. Sasaki

Chapter 9 Imprinting polymerisation for recognition and separation of metal ions Original Research Article
Pages 245-269
Kazuhiko Tsukagoshi, Masaharu Murata, Mizuo Maeda

Chapter 10 Bio-imprinting: polymeric receptors with and for biological macromolecules Original Research Article
Pages 271-294
Pradeep K. Dhal, Mohan G. Kulkarni, Raghunath A. Mashelkar

Chapter 11 Surface imprinting of microorganisms Original Research Article
Pages 295-304
Natalia Perez, Cameron Alexander, Evgeny N. Vulfson

Chapter 12 Polymerisation techniques for the formation of imprinted beads Original Research Article
Pages 305-324
Andrew G. Mayes

Chapter 13 Techniques for the in situ preparation of imprinted polymers Original Research Article
Pages 325-340
Jun Matsui, Toshifumi Takeuchi

Chapter 14 Application of molecularly imprinted polymers in competitive ligand binding assays for analysis of biological samples Original Research Article
Pages 341-354
Lars I. Andersson

Chapter 15 Molecularly imprinted polymers in solid phase extractions Original Research Article
Pages 355-375
Börje Sellergren, Francesca Lanza

Chapter 16 Capillary electrochromatography based on molecular imprinting Original Research Article
Pages 377-393
Leif Schweitz, Staffan Nilsson

Chapter 17 Molecularly imprinted polymers in enantiomer separations Original Research Article
Pages 395-415
Maria Kempe

Chapter 18 Biomimetic electrochemical sensors based on molecular imprinting Original Research Article
Pages 417-440
Dario Kriz, Richard J. Ansell

Chapter 19 Ionic sensors based on molecularly imprinted polymers Original Research Article
Pages 441-465
George M. Murray, O. Manuel Uy

Chapter 20 Toward optical sensors for biologically active molecules Original Research Article
Pages 467-501
Scott Mcniven, Isao Karube

Chapter 21 Non-covalent molecularly imprinted sensors for vapours, polyaromatic hydrocarbons and complex mixtures Original Research Article
Pages 503-525
Franz L. Dickert, Oliver Hayden

Index
Pages 527-557