Novel Optical Resolution Technologies

Gérard Coquerel (auth.), Kenichi Sakai, Noriaki Hirayama, Rui Tamura (eds.)3540463178, 9783540463177

G. Coquerel: Preferential Crystallization.-

R. Tamura, H. Takahashi, D. Fujimoto, T. Ushio: Mechanism and Scope of Preferential Enrichment, a Symmetry-Breaking Enantiomeric Resolution Phenomenon.-

R. Yoshioka: Racemization, Optical Resolution, and Crystallization-Induced Asymmetric Transformation of Amino Acids and Pharmaceutical Intermediates.-

F. Faigl, J. Schindler, E. Fogassy: Advantages of Structural Similarities of the Reactants in Optical Resolution Processes.-

R.M. Kellogg , B. Kaptein, T.R. Vries: Dutch Resolution of Racemates and the Roles of Solid Solution Formation and Nucleation Inhibition.-

K. Sakai, R. Sakurai, H. Nohira: New Resolution Technologies Controlled by Chiral Discrimination Mechanisms.-

K. Sakai, R. Sakurai, N. Hirayama: Molecular Mechanisms of Dielectrically Controlled Resolution (DCR).-

H. Murakami: From Racemates to Single Enantiomers – Chiral Synthetic Drugs over the Recent 20 Years

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Table of contents :
Front Matter….Pages I-XIV
Preferential Crystallization….Pages 1-51
Mechanism and Scope of Preferential Enrichment, a Symmetry-Breaking Enantiomeric Resolution Phenomenon….Pages 53-82
Racemization, Optical Resolution and Crystallization-Induced Asymmetric Transformation of Amino Acids and Pharmaceutical Intermediates….Pages 83-132
Advantages of Structural Similaritiesof the Reactants in Optical Resolution Processes….Pages 133-157
Dutch Resolution of Racemates and the Roles of Solid Solution Formation and Nucleation Inhibition….Pages 159-197
New Resolution Technologies Controlled by Chiral Discrimination Mechanisms….Pages 199-231
Molecular Mechanisms of Dielectrically Controlled Resolution (DCR)….Pages 233-271
From Racemates to Single Enantiomers – Chiral Synthetic Drugs over the last 20 Years….Pages 273-299
Back Matter….Pages 301-313