Introduction to Macromolecular Crystallography

Alexander McPherson0470185902, 978-0-470-18590-2

An overview of macromolecular crystallography — Crystallization of macromolecules — The nature of crystals: symmetry and the unit cell — Waves and their properties — Diffraction from points, planes, molecules, and crystals — Interpretation of diffraction patterns — Data collection — Solving the phase problem — Interpreting Patterson maps — Electron density, refinement, and difference Fourier maps

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Table of contents :
CONTENTS……Page 5
PREFACE……Page 9
AN OVERVIEW OF MACROMOLECULAR CRYSTALLOGRAPHY……Page 11
THE NATURE OF CRYSTALS: SYMMETRY AND THE UNIT CELL……Page 60
WAVES AND THEIR PROPERTIES……Page 87
DIFFRACTION FROM POINTS, PLANES, MOLECULES, AND CRYSTALS……Page 103
INTERPRETATION OF DIFFRACTION PATTERNS……Page 135
DATA COLLECTION……Page 160
SOLVING THE PHASE PROBLEM……Page 180
INTERPRETING PATTERSON MAPS……Page 203
ELECTRON DENSITY, REFINEMENT, AND DIFFERENCE FOURIER MAPS……Page 221
BIBLIOGRAPHY……Page 248
INDEX……Page 253