Encyclopedic Reference of Cancer Research

Manfred Schwab9783540665274, 3-540-66527-7

“This encyclopedic reference provides rapid access to focused information on topics of cancer research for clinicians, research scientists and advanced students. With an A-Z format of about 2000 entries, over 220 contributing authors provide a complete reference to cancer. The merging of different basic and clinical scientific disciplines towards the common goal of fighting cancer makes such a comprehensive reference source all the more necessary, providing definitions of common acronyms and short definitions of related terms and processes in the form of keyword entries. In addition to the keyword entries, there are detailed entries termed essays, which provide comprehensive information on syndromes, genes and molecules, and processes and methods. Each essay is well-structured, with extensive cross-referencing between all entries. The book is accompanied by a CD-ROM, which contains the full text and facilitates searches.

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Table of contents :
Encyclopedic Reference of Cancer……Page 1
Content……Page 0
Front Matter……Page 2
Bibliographic information……Page 5
Preface……Page 6
List of Contributors……Page 8
AAV……Page 25
ABC Transporter……Page 30
Acidosis……Page 31
Acute Lymphoblastic —Leukemia……Page 32
Acute Lymphocytic Leukemia……Page 35
Adaptive Response……Page 38
Adenocarcinoma……Page 43
Adenylyl Cyclase……Page 47
Adherens Junctions……Page 48
Adjuvant Therapy……Page 55
Adoptive Immunotherapy……Page 56
Aflatoxins……Page 58
AKT……Page 59
ALA……Page 61
-Interferon……Page 62
Alternative Lengthening of —Telomeres……Page 63
Amino Acid Single Letter Code……Page 64
AML-1/ETO/CBF/TEL in Chromosomal Translocations……Page 65
Amplification……Page 67
Aneuploidy……Page 69
Angiogenesis……Page 75
Antigen……Page 79
Antioxidant Defences……Page 80
AP-1……Page 84
AP-2……Page 91
APC Gene in Familial —Adenomatous Polyposis……Page 92
Apoptosis……Page 97
Asbestos……Page 101
Astrocytoma……Page 102
ATM Protein……Page 103
ATR……Page 106
Autonomic Nervous System……Page 107
Autophagy……Page 108
Balanced Translocation……Page 111
Basal Cell Carcinoma……Page 112
Basal Cell Nevus Syndrome……Page 115
BAX……Page 116
B-cell Tumours……Page 117
BCL-2……Page 122
BCL6……Page 125
BCR-ABL1……Page 130
Beckwith-Wiedemann Syndrome Associated Childhood Tumours……Page 135
Benign Tumor……Page 142
Biomarkers……Page 143
Birt Hogg Dube Syndrome……Page 146
Bladder Cancer……Page 147
Blast Crisis……Page 153
Brachytherapy……Page 154
Brain Tumors……Page 155
BRCA2……Page 158
Breast Cancer……Page 163
Breast Cancer Genes BRCA1 and BRCA2……Page 165
BRMS1……Page 169
Burkitt Lymphoma Cell Lines……Page 170
Cachexia……Page 171
Cadherin……Page 173
Camptothecin……Page 174
Cancer Chemoprevention……Page 176
Carcinoembryonic Antigen……Page 181
Caretaker……Page 190
Caspase 3……Page 191
Caspase 9……Page 192
C-bandless Chromosome……Page 193
CD15……Page 194
CD44……Page 195
CDC7……Page 197
CDKN2A……Page 198
Cell Adhesion Molecules……Page 205
Cell-cycle Checkpoint……Page 211
Cell-cycle Targets for Cancer Therapy……Page 212
Cervical Cancers……Page 216
Checkpoint……Page 218
Chemotherapy of Cancer, progress and perspectives……Page 219
Cholangiocarcinoma……Page 223
Chromophore-assisted Laser Inactivation……Page 226
Chromosome Condensation……Page 230
Chronic Lymphocytic Leukemia (B-CLL)……Page 231
CKI……Page 234
CML……Page 235
Coiled-coil Domain……Page 236
Colon Cancer……Page 237
Complementary DNA……Page 243
Constitutive Genes……Page 244
Cot……Page 245
CpG Islands……Page 251
CREB……Page 253
CT……Page 254
Cyclin D……Page 255
Cyclin-dependent Kinase Inhibitor 1B……Page 258
Cyclooxygenase-2 in Colorectal Cancer……Page 259
Cytogenetics……Page 260
Cytosol……Page 261
Cytotoxic T Lymphocytes……Page 262
DCC……Page 263
Deleted in Malignant Brain Tumors 1……Page 264
Desmoid……Page 268
Desmosome……Page 269
Detoxification……Page 271
Diet and Cancer……Page 274
Diplopia……Page 275
DNA Adducts……Page 276
Dormancy……Page 277
DPC4……Page 278
Drosophila melanogaster……Page 282
Dysplastic Naevus Syndrome……Page 283
E2F……Page 285
E-box……Page 296
EBV……Page 300
E-cadherin……Page 301
Effector Cell Protease Receptor-1……Page 305
EGFR……Page 306
Endocytosis……Page 312
Endosomal Compartment……Page 316
Ependymoma……Page 317
Epoxide Hydrolase……Page 319
Epstein-Barr Virus……Page 320
ERBB2……Page 324
Erythropoietin……Page 325
ES……Page 327
Esophageal Cancer……Page 328
Estrogenic Hormones and Cancer……Page 330
ETS Transcription Factors……Page 333
Ewing Sarcoma……Page 336
EWS……Page 338
Excision Repair……Page 341
Extracellular Matrix……Page 342
Extramedullary……Page 343
Familial Cancer……Page 345
Fanconi Anemia……Page 346
FAS……Page 351
Fermentation Products……Page 352
FHIT……Page 353
Fibroids……Page 355
FISH……Page 360
FLP/FRT System……Page 361
Fluorescence Diagnostics……Page 362
Follicular Lymphoma……Page 364
Fragile Site……Page 365
FRAXA……Page 367
Gain-of-function Mutation……Page 369
GAP Junctions……Page 370
Gastrinoma……Page 371
GC-MS……Page 373
GEF……Page 374
Gene Therapy……Page 375
Genetic Disorders Associated with Cancer Predisposition and Chromosomal Instability