Harper’s Illustrated Biochemistry

Robert K. Murray, Darryl K. Granner, Peter A. Mayes, Victor W. Rodwell9780071389013, 0-07-138901-6

Extensively revised and updated, this authoritative biochemistry text is known worldwide for its comprehensive and up-to-date coverage. Extensively illustrated and user-friendly, the text offers examples pf how knowledge of biochemistry is essential for understanding the molecular basis of health and disease. The 26th edition also features expanded content on results of the Human Genome Project. Perfect as both text and USMLE review.

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Table of contents :
Front Matter……Page 1
Preface……Page 5
Table of Contents……Page 7
1. Biochemistry & Medicine……Page 11
2. Water & pH……Page 15
3. Amino Acids & Peptides……Page 24
4. Proteins: Determination of Primary Structure……Page 31
5. Proteins: Higher Orders of Structure……Page 40
6. Proteins: Myoglobin & Hemoglobin……Page 50
7. Enzymes: Mechanism of Action……Page 59
8. Enzymes: Kinetics……Page 70
9. Enzymes: Regulation of Activities……Page 82
10. Bioenergetics: The Role of ATP……Page 90
11. Biologic Oxidation……Page 96
12. The Respiratory Chain & Oxidative Phosphorylation……Page 102
13. Carbohydrates of Physiologic Significance……Page 112
14. Lipids of Physiologic Significance……Page 121
15. Overview of Metabolism……Page 132
16. The Citric Acid Cycle: The Catabolism of Acetyl-CoA……Page 140
17. Glycolysis & the Oxidation of Pyruvate……Page 146
18. Metabolism of Glycogen……Page 155
19. Gluconeogenesis & Control of the Blood Glucose……Page 163
20. The Pentose Phosphate Pathway & Other Pathways of Hexose Metabolism……Page 173
21. Biosynthesis of Fatty Acids……Page 183
22. Oxidation of Fatty Acids: Ketogenesis……Page 190
23. Metabolism of Unsaturated Fatty Acids & Eicosanoids……Page 200
24. Metabolism of Acylglycerols & Sphingolipids……Page 207
25. Lipid Transport & Storage……Page 215
26. Cholesterol Synthesis, Transport & Excretion……Page 229
27. Integration of Metabolism—the Provision of Metabolic Fuels……Page 241
28. Biosynthesis of the Nutritionally Nonessential Amino Acids……Page 247
29. Catabolism of Proteins & of Amino Acid Nitrogen……Page 252
30. Catabolism of the Carbon Skeletons of Amino Acids……Page 259
31. Conversion of Amino Acids to Specialized Products……Page 274
32. Porphyrins & Bile Pigments……Page 280
33. Nucleotides……Page 296
34. Metabolism of Purine & Pyrimidine Nucleotides……Page 303
35. Nucleic Acid Structure & Function……Page 313
36. DNA Organization, Replication & Repair……Page 324
37. RNA Synthesis. Processing & Modification……Page 351
38. Protein Synthesis & the Genetic Code……Page 368
39. Regulation of Gene Expression……Page 384
40. Molecular Genetics, Recombinant DNA & Genomic Technology……Page 406
41. Membranes: Structure & Function……Page 425
42. The Diversity of the Endocrine System……Page 444
43. Hormone Action & Signal Transduction……Page 466
44. Nutrition, Digestion & Absorption……Page 484
45. Vitamins & Minerals……Page 491
46. Intracellular Traffic & Sorting of Proteins……Page 508
47. Glycoproteins……Page 524
48. The Extracellular Matrix……Page 545
49. Muscle & the Cytoskeleton……Page 566
50. Plasma Proteins & Immunoglobulins……Page 590
51. Hemostasis & Thrombosis……Page 608
52. Red & White Blood Cells……Page 619
53. Metabolism of Xenobiotics……Page 636
54. The Human Genome Project……Page 643
Appendix……Page 649
A……Page 652
B……Page 656
C……Page 658
D……Page 663
E……Page 665
F……Page 668
G……Page 669
H……Page 673
I……Page 676
K……Page 678
L……Page 679
M……Page 681
N……Page 684
O……Page 686
P……Page 687
R……Page 692
S……Page 694
T……Page 697
V……Page 700
W……Page 701
Z……Page 702