Parapoxvirus (Orf Virus) IL-10 Homolog

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McFadden G., Moyer R.

To date, viral homologs of cellular IL-10 have been discovered in several herpesviruses and one poxvirus, namely orf virus of sheep. The poxvirus vIL-10 is expressed as a secreted ligand with biological properties similar to the cellular IL-10, and is believed to play an important immunoregulatory role for orf virus.

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