Nutrition and Metabolism: Underlying Mechanisms and Clinical Consequences

Christos S. Mantzoros (auth.), Christos S. Mantzoros (eds.)1603274529, 978-1-60327-452-4, 978-1-60327-453-1

Nutrition and Metabolism: Underlying Mechanisms and Clinical Consequences brings together internationally recognized experts to comprehensively review our current understanding of how nutrition interacts with the genetic substrate as well as environmental-exogenous factors, including physical activity or the lack thereof, to result in insulin resistance and the metabolic syndrome. After presenting the scope of the problem, the first major part of the book is devoted to genetics and pathophysiology, the second part of the book presents the public health perspective of the most prevalent problems associated with nutrition and the metabolic syndrome, whereas the third major part of the book focuses on clinical assessment and management of the main disease states associated with inappropriate nutrition and the metabolic syndrome. Finally, general information useful for both clinicians and researchers alike is presented in the Appendix. Nutrition and Metabolism: Underlying Mechanisms and Clinical Consequences offers the reader an up-to-date and authoritative review of the major scientific and clinical aspects of the overlapping areas between nutrition and metabolism.

Table of contents :
Front Matter….Pages i-xx
Front Matter….Pages 1-1
Nutrition and the Metabolic Syndrome: A Twenty-First-Century Epidemic of Obesity and Eating Disorders….Pages 3-7
Genes and Gene–Environment Interactions in the Pathogenesis of Obesity and the Metabolic Syndrome….Pages 11-39
Environmental Inputs, Intake of Nutrients, and Endogenous Molecules Contributing to the Regulation of Energy Homeostasis….Pages 41-75
Central Integration of Environmental and Endogenous Signals Important in the Regulation of Food Intake and Energy Expenditure….Pages 77-106
Front Matter….Pages 106-106
Insulin Resistance in States of Energy Excess: Underlying Pathophysiological Concepts….Pages 107-122
Targeting Childhood Obesity Through Lifestyle Modification….Pages 125-133
Diet and Physical Activity in the Prevention of Obesity….Pages 135-147
Diet and Exercise in the Prevention and Management of the Metabolic Syndrome….Pages 149-160
Front Matter….Pages 160-160
Diet and Physical Activity in Cancer Prevention….Pages 161-192
Food Guide Pyramids and the 2005 MyPyramid….Pages 195-207
Nutrition Recommendations for the General Population: Where Is the Science?….Pages 209-220
Nutrition Recommendations and Interventions for Subjects with Cardiovascular Disease….Pages 221-244
Front Matter….Pages 244-244
Medical Nutrition Therapy in the Treatment of Type 1 and Type 2 Diabetes….Pages 245-260
Mediterranean Diet in Disease Prevention: Current Perspectives….Pages 263-278
Lifestyle and Pharmacology Approaches for the Treatment of Hypertension and Hyperlipidemia….Pages 279-288
Diagnosis, Evaluation, and Medical Management of Obesity and Diabetes….Pages 289-328
Front Matter….Pages 328-328
Surgical Management of Obesity and Postoperative Care….Pages 329-345
Long-Term Impact of Weight Loss on Obesity and Obesity-Associated Comorbidities….Pages 347-368
Methods for Classifying, Diagnosing, and Monitoring Obesity….Pages 371-383
Methods for Classifying, Diagnosing, and Monitoring Type II Diabetes….Pages 385-391
Front Matter….Pages 392-392
Major Nutrition Recommendations and Interventions for Subjects with Hyperlipidemia, Hypertension, and/or Diabetes….Pages 393-404
Front Matter….Pages 406-406
Resources….Pages 407-413
Back Matter….Pages 415-423