Strategies in regenerative medicine: integrating biology with materials design

Stephen F. Badylak, Alan J. Russell, Matteo Santin (auth.), Matteo Santin (eds.)9780387746593, 0387746595

This authoritative book offers a detailed overview of present and future tissue engineering approaches and their contribution to regenerative medicine. It combines comprehensive reviews of the biology and materials science underlying the development and regeneration of different types of tissues with descriptions of current and future strategies in regenerative medicine to meet clinical needs. Each chapter includes typical examples of methodologies and technical solutions as the basis for the most recent scientific findings and biomedical products, tables as mini-databases summarizing the most recent findings, and links to specific websites in the main body of the text to complement a traditional reference list. Strategies in Regenerative Medicine: Integrating Biology with Materials Design covers topics from basic biology and materials science to the link between biological processes in tissue regeneration and biomedical device/tissue engineering product performance.

Table of contents :
Front Matter….Pages 1-15
Introduction: History of Regenerative Medicine….Pages 1-13
Soft Tissues Characteristics and Strategies for Their Replacement and Regeneration….Pages 1-40
Biomaterials for Tissue Engineering of Hard Tissues….Pages 1-42
Biomimetic and Bio-responsive Materials in Regenerative Medicine….Pages 1-58
Clinical Approaches to Skin Regeneration….Pages 1-33
Angiogenesis in Development, Disease, and Regeneration….Pages 1-41
Tissue Engineering of Small– and Large– Diameter Blood Vessels….Pages 1-30
Pancreas Biology, Pathology, and Tissue Engineering….Pages 1-21
The Holy Grail of Hepatocyte Culturing and Therapeutic Use….Pages 1-38
Peripheral Nerve Injury, Repair, and Regeneration….Pages 1-20
Therapeutic Strategies in Ocular Tissue Regeneration: The Role of Stem Cells….Pages 1-25
Cartilage Development, Physiology, Pathologies, and Regeneration….Pages 1-27
Basic Science and Clinical Strategies for Articular Cartilage Regeneration/Repair….Pages 1-36
Bone Biology: Development and Regeneration Mechanisms in Physiological and Pathological Conditions….Pages 1-18
Clinical Applications of Bone Tissue Engineering….Pages 1-18
Conclusions: Towards High-Performance and Industrially Sustainable Tissue Engineering Products….Pages 1-27
Back Matter….Pages 1-12