Biomembrane frontiers: nanostructures, models, and the design of life

Amalie L. Frischknecht, Laura J. D. Frink (auth.), Roland Faller, Marjorie L. Longo, Subhash H. Risbud, Thomas Jue (eds.)9781607613138, 1607613131, 160761314X, 9781607613145

HANDBOOK OF MODERN BIOPHYSICS

Series Editor Thomas Jue, PhD

Handbook of Modern Biophysics brings current biophysics topics into focus, so that biology, medical, engineering, mathematics, and physical-science students or researchers can learn fundamental concepts and the application of new techniques in addressing biomedical challenges. Chapters explicate the conceptual framework of the physics formalism and illustrate the biomedical applications. With the addition of problem sets, guides to further study, and references, the interested reader can continue to explore independently the ideas presented.

Volume II: Biomembrane Frontiers: Nanostructures, Models, and the Design of Life

Editors: Roland Faller, PhD, Thomas Jue, PhD, Marjorie L. Longo, PhD, and Subhash H. Risbud, PhD

In Biomembrane Frontiers: Nanostructures, Models, and the Design of Life, prominent researchers have established a foundation for the study of biophysics related to the following topics:

Perspectives: Complexes in Liquids, 1900–2008

Molecular Theory Applied to Lipid Bilayers and Lipid–Protein Interactions

Membrane Elasticity and Mediated Interactions in Continuum Theory: A Differential Geometric Approach

Structure and Dynamics of Lipid Monolayers: Theory and Applications

Multiscale Modeling of Supported Lipid Bilayers

Collective Dynamics in Lipid Membranes:

From Pore Formation to Flip-Flops

Spatiotemporal Organization of Spin-Coated Supported Model Membranes

Nanopore Analysis of Nucleic Acids: Single-Molecule
Studies of Molecular Dynamics, Structure, and Base Sequence

Complex Applications of Simple FRAP on Membranes

Punching Holes in Membranes: How Oligomeric
Pore-Forming Proteins and Lipids Cooperate to Form Aqueous Channels in Membranes

Morphogens, Membranes and Mechanotransduction in Articular Cartilage

Lifecycle of a Lipoprotein from a Biophysical Perspective

Targeting Apolipoproteins in Magnetic Resonance Imaging

About the Editors

The editors are internationally recognized biomembrane experts and have published extensively on the structure, dynamics, and function of model and cellular membranes. Roland Faller is an Associate Professor and the Joe & Essie Smith Endowed Chair in the Department of Chemical Engineering & Materials Science at the University of California Davis. He develops and uses modern molecular simulation techniques for soft condensed matter systems, particularly biomembranes. Thomas Jue is a Professor in the Department of Biochemistry and Molecular Medicine at the University of California Davis. He develops and applies magnetic resonance techniques to study biochemical regulation in vivo. Marjorie L. Longo is a professor in the Department of Chemical Engineering and Materials Science at the University of California Davis. She applies microscopy techniques to study surface and transport properties of lipid bilayers and monolayers. Subhash H. Risbud is the Blacutt-Underwood Distinguished Professor of Materials Science in the Department of Chemical Engineering and Materials Science at the University of California at Davis and a Visiting Professor at Stanford University. His group develops new materials for nano- and biotechnology. The materials include glasses, ceramics, and nanoporous substrates for biological membranes.

Table of contents :
Front Matter….Pages 1-19
Molecular Theory Applied to Lipid Bilayers and Lipid–Protein Interactions….Pages 1-39
Membrane Elasticity and Mediated Interactions in Continuum Theory: A Differential Geometric Approach….Pages 41-74
Structure and Dynamics of Lipid Monolayers: Theory and Applications….Pages 75-99
Multiscale Modeling of Supported Lipid Bilayers….Pages 101-120
Collective Dynamics in Lipid Membranes: From Pore Formation to Flip-Flops….Pages 121-139
Spatiotemporal Organization of Spin-Coated Supported Model Membranes….Pages 141-170
Nanopore Analysis of Nucleic Acids: Single-Molecule Studies of Molecular Dynamics, Structure, and Base Sequence….Pages 171-186
Complex Applications of Simple FRAP on Membranes….Pages 187-221
Punching Holes in Membranes: How Oligomeric Pore-Forming Proteins and Lipids Cooperate to Form Aqueous Channels in Membranes….Pages 223-262
Morphogens, Membranes and Mechanotransduction in Articular Cartilage….Pages 263-273
Lifecycle of a Lipoprotein from a Biophysical Perspective….Pages 275-284
Targeting Apolipoproteins in Magnetic Resonance Imaging….Pages 285-297
Back Matter….Pages 1-25