Data mining in bioinformatics

Jason T. L. Wang, Mohammed J. Zaki, Hannu Toivonen, Dennis E. Shasha9781852336714, 1852336714

The goal of this book is to help readers understand state-of-the-art techniques in biological data mining & data management & includes topics such as: * preprocessing tasks such as data cleaning & data integration as applied to biological data * classification & clustering techniques for microarrays * comparison of RNA structures based on string properties & energetics * discovery of the sequence characteristics of different parts of the genome * mining of haplotypes to find disease markers * sequencing of events leading to the folding of a protein * inference of the subcellular location of protein activity * classification of chemical compounds based on structure * special purpose metrics & index structures for phylogenetic applications * a new query language for protein searching based on the shape of proteins * very fast indexing schemes for sequences & pathways Aimed at computer scientists, necessary biology is explained.