Analytical Profiles of Drug Substances and Excipients, Vol. 29

Harry G. Brittain (Ed.)978-0-12-260829-2

Although the official compendia define a drug substance as to identity, purity, strength, and quality, they normally do not provide other physical or chemical data, nor do they list methods of synthesis or pathways of physical or biological degradation and metabolism. Such information is scattered throughout the scientific literature and the files of pharmaceutical laboratories. Analytical Profiles of Drug Substances and Excipients, brings the latest information together in one source.•Represents a very important contribution to the practice of pharmaceutical analysis• Presents an excellent overview of physical, chemical, and biomedical properties of some regularly prescribed drugs• Each volume in the series contains a cumulative index

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Table of contents :
Content:
Editorial Board
Page ii

Edited by
Page iii

Copyright page
Page iv

Affiliations of Editors and Contributors
Pages vii-viii

Profiles of Drug Substances, Excipients, and Related Methodology Original Research Article
Pages 1-5
Harry G. Brittain

Aspartame Original Research Article
Pages 7-55
Richard J. Prankerd

Edetic Acid [Ethylenediamine Tetraacetic Acid, Edta] Original Research Article
Pages 57-104
F. Belal, Abdullah A. Al-Badr

Etodolac Original Research Article
Pages 105-147
Ketan P. Shah, Kavita Gumbhir-Shah, Harry G. Brittain

Eugenol Original Research Article
Pages 149-177
Mochammad Yuwono, Siswandono, Achmad Fuad Hafid, Achmad Toto Poernomo, Mangestuti Agil, Gunawan Indrayanto, Siegfried Ebel

Mandelic Acid Original Research Article
Pages 179-211
Harry G. Brittain

Pantoprazole Sodium Original Research Article
Pages 213-259
Adrian A. Badwan, Lina N. Nabulsi, M.M. Al Omari, Nidal H. Daraghmeh, Mahmoud K. Ashour, Ahmad M. Abdoh, A.M.Y. Jaber

Spironolactone Original Research Article
Pages 261-320
Badraddin M.H. Al-Hadiya, Fathalla Belal, Yousif A. Asiri, Othman A. Gubara

Cumulative Index
Pages 321-327