Cell Communication in Nervous and Immune System

Eckart D. Gundelfinger, Constanze Seidenbecher, Burkhart Schraven9783540368281, 3-540-36828-0

At first glance, the nervous and immune systems appear very different. However, both systems have developed mechanisms for memory formation – though of quite different quality and significance for the organism. One striking example is that both systems form and communicate via synapses armed with similar sets of proteins. This collection of reviews, contributed by internationally recognized immunologists and molecular and cellular neurobiologists, puts side by side cellular communication devices and signaling mechanisms in the immune and nervous systems and discusses mechanisms of interaction between the two systems, the significance of which has only recently been fully appreciated.

---

Table of contents :
Cover……Page 1
Series Title Page……Page 2
Inside Cover……Page 3
Copyright……Page 4
Preface……Page 5
Contents……Page 9
Molecular Organization and Assembly of the Postsynaptic Density of Excitatory Brain Synapses……Page 15
Molecular Organization and Assembly of the Central Inhibitory Postsynapse……Page 38
Molecular Organization and Assembly of the Presynaptic Active Zone of Neurotransmitter Release……Page 61
Extracellular Matrix and Synaptic Functions……Page 81
Electrical Synapses – Gap Junctions in the Brain……Page 110
Neuron-Glia Interactions at the Node of Ranvier……Page 140
Cognate Interaction Between Endothelial Cells and T Cells……Page 161
Impact of the Immunological Synapse on T Cell Signaling……Page 184
The Biophysics of T Lymphocyte Activation In Vitro and In Vivo……Page 208
Molecular Regulation of Cytoskeletal Rearrangements During T Cell Signalling……Page 228
Membrane-Proximal Signaling Events in Beta-2 Integrin Activation……Page 254
Regulation of Immune Cell Entry into the Central Nervous System……Page 267
Cell–cell communication by Endocannabinoids during Immune Surveillance of the Central Nervous System……Page 289
Subject Index……Page 314