Molecular Biology

Robert F. Weaver9780072345179, 0072345179, 0071122877

Molecular Biology, 2/e emphasizes the experimental data and results that support the concepts of molecular biology: DNA transcription, translation, replication, and repair. Experimental methods are extensively covered. The text presumes a prior course in general genetics.

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Table of contents :
Front Matter……Page 1
Preface……Page 2
Guide to Experimental Techniques in Molecular Biology……Page 4
1. A Brief History……Page 6
2. The Molecular Nature of Genes……Page 21
3. An Introduction to Gene Function……Page 43
4. Molecular Cloning Methods……Page 64
5. Molecular Tools for Studying Genes and Gene Activity……Page 96
6. The Transcription Apparatus of Prokaryotes……Page 138
7. Operons: Fine Control of Prokaryotic Transcription……Page 180
8. Major Shifts in Prokaryotic Transcription……Page 210
9. DNA-Protein Interactions in Prokaryotes……Page 236
10. Eukaryotic RNA Polymerases and Their Promoters……Page 266
11. General Transcription Factors in Eukaryotes……Page 302
12. Transcription Activators in Eukaryotes……Page 347
13. Chromatin Structure and Its Effects on Transcription……Page 385
14. Splicing……Page 423
15. Capping and Polyadenylation……Page 467
16. Other Events……Page 502
17. Initiation……Page 533
18. Elongation and Termination……Page 572
19. Ribosomes and Transfer RNA……Page 611
20. DNA Replication I: Basic Mechanism and Enzymology……Page 647
21. DNA Replication II: Detailed Mechanism……Page 689
22. Homologous Recombination……Page 722
23. Site-Specific Recombination and Transposition……Page 752
24. Genomics……Page 789
Glossary……Page 824
Index……Page 847