Color Atlas of Pharmacology

Heinz Luellmann, Klaus Mohr, Lutz Hein, Detlef Bieger9781588903327, 1-58890-332-X, 313781703X

The pocket atlas provides quick information on general pharmacology, systems pharmacology, and therapy for selected diseases, with pages of explanatory text facing pages of color illustrations by Jügen Wirth (visual communications, U. of Applied Sciences, Darmstadt, Germany). Translated by Detlef Bieger from the 2004 fifth edition of Taschenatlas der Pharmakologie. The authors state that they have no financial interests or other relationships that would influence the content.

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Table of contents :
Color Page……Page 1
Title Page……Page 3
ISBN 158890332X……Page 4
Preface to the 3rd edition……Page 5
General Pharmacology……Page 6
Systems Pharmacology……Page 7
Therapy of Selected Diseases……Page 9
Subject Index……Page 10
Abbreviations……Page 11
General Pharmacology……Page 13
History of Pharmacology……Page 14
The Aims of Isolating Active Principles……Page 16
European Plants as Sources of Effective Medicines……Page 18
Drug Development……Page 20
Congeneric Drugs and Name Diversity……Page 22
Oral Dosage Forms……Page 24
Drug Administration by Inhalation……Page 26
Dermatological Agents……Page 28
From Application to Distribution in the Body……Page 30
Potential Targets of Drug Action……Page 32
External Barriers of the Body……Page 34
Blood–Tissue Barriers……Page 36
Membrane Permeation……Page 38
PossibleModes of Drug Distribution……Page 40
Binding to Plasma Proteins……Page 42
The Liver as an Excretory Organ……Page 44
Biotransformation of Drugs……Page 46
Drug Metabolism by Cytochrome P450……Page 50
The Kidney as an Excretory Organ……Page 52
Presystemic Elimination……Page 54
Drug Concentration in the Body as a Function of Time—First Order (Exponential) Rate Processes……Page 56
Time Course of Drug Concentration in Plasma……Page 58
Time Course of Drug Plasma Levels during Irregular Intake (B)……Page 60
Change in Elimination Characteris-tics during Drug Therapy (B)……Page 62
Dose–Response Relationship……Page 64
Concentration–Effect Curves (B)……Page 66
Concentration–Binding Curves……Page 68
Types of Binding Forces……Page 70
Other Forms of Antagonism……Page 72
Enantioselectivity of Drug Action……Page 74
Receptor Types……Page 76
Mode of Operation of G-Protein-coupled Receptors……Page 78
Time Course of Plasma Concentra-tion and Effect……Page 80
Undesirable Drug Effects, Side Effects……Page 82
Drug Allergy……Page 84
Cutaneous Reactions……Page 86
Drug Toxicity in Pregnancy and Lactation……Page 88
Pharmacogenetics……Page 90
Placebo (A)……Page 92
Systems Pharmacology……Page 95
Sympathetic Nervous System……Page 96
Adrenergic Synapse……Page 98
Metabolic Effects……Page 100
Structure–Activity Relationships of Sympathomimetics……Page 102
Indirect Sympathomimetics……Page 104
Sympatholytics……Page 106
Blockers)……Page 108
Blockers……Page 110
Antiadrenergics……Page 112
Parasympathetic Nervous System……Page 114
Cholinergic Synapse……Page 116
Parasympathomimetics……Page 118
Parasympatholytics……Page 120
Aids for Smoking Cessation……Page 124
Consequences of Tobacco Smoking……Page 126
Dopamine……Page 128
Histamine Effects and Their Pharmacological Properties……Page 130
Serotonin……Page 132
Vasodilators—Overview……Page 134
Organic Nitrates……Page 136
Calcium Antagonists……Page 138
ACE Inhibitors……Page 140
Drugs Used to Influence Smooth Muscle Organs……Page 142
Cardiac Drugs……Page 144
Cardiac Glycosides……Page 146
Antiarrhythmic Drugs……Page 148
Electrophysiological Actions of Antiarrhythmics of the Na+- Channel Blocking Type……Page 150
Drugs for the Treatment of Anemias……Page 152
Iron Compounds……Page 154
Prophylaxis and Therapy of Thromboses……Page 156
Possibilities for Interference (B)……Page 158
Hirudin and Derivatives (B)……Page 160
Fibrinolytics……Page 162
Formation, Activation, and Aggregation of Platelets (B)……Page 164
Presystemic Effect of ASA……Page 166
Plasma Volume Expanders……Page 168
Lipid-lowering Agents……Page 170
Diuretics—An Overview……Page 174
Osmotic Diuretics (B)……Page 176
Diuretics of the Sulfonamide Type……Page 178
Vasopressin and Derivatives (B)……Page 180
Drugs for Gastric and Duodenal Ulcers……Page 182
Laxatives……Page 186
Antidiarrheal Agents……Page 192
Drugs Affecting Motor Function……Page 194
Nondepolarizing Muscle Relaxants……Page 196
Depolarizing Muscle Relaxants……Page 198
Antiparkinsonian Drugs……Page 200
Antiepileptics……Page 202
Pain Mechanisms and Pathways……Page 206
Eicosanoids……Page 208
Nonsteroidal Anti-inflammatory Drugs (NSAIDs)……Page 210
Cyclooxygenase (COX) Inhibitors……Page 212
Local Anesthetics……Page 214
Opioid Analgesics—Morphine Type……Page 220
General Anesthesia and General Anesthetic Drugs……Page 226
Inhalational Anesthetics……Page 228
Injectable Anesthetics……Page 230
Sedatives, Hypnotics……Page 232
Benzodiazepines……Page 234
Pharmacokinetics of Benzodiazepines……Page 236
Therapy of Depressive Illness……Page 238
Mania……Page 242
Therapy of Schizophrenia……Page 244
Psychotomimetics (Psychedelics, Hallucinogens)……Page 248
Hypothalamic and Hypophyseal Hormones……Page 250
Thyroid Hormone Therapy……Page 252
Hyperthyroidism and Antithyroid Drugs……Page 254
Glucocorticoid Therapy……Page 256
Androgens, Anabolic Steroids, Antiandrogens……Page 260
Follicular Growth and Ovulation, Estrogen and Progestin Production……Page 262
Oral Contraceptives……Page 264
Antiestrogen and Antiprogestin Active Principles……Page 266
Aromatase Inhibitors……Page 268
Insulin Formulations……Page 270
Treatment of Insulin-dependent Diabetes Mellitus……Page 272
Treatment of Maturity-Onset (Type II) Diabetes Mellitus……Page 274
Oral Antidiabetics……Page 276
Drugs for Maintaining Calcium Homeostasis……Page 278
Drugs for Treating Bacterial Infections……Page 280
Inhibitors of Cell Wall Synthesis……Page 282
Inhibitors of Tetrahydrofolate Synthesis……Page 286
Inhibitors of DNA Function……Page 288
Inhibitors of Protein Synthesis……Page 290
Drugs for Treating Mycobacterial Infections……Page 294
Drugs Used in the Treatment of Fungal Infections……Page 296
Chemotherapy of Viral Infections……Page 298
Drugs for the Treatment of AIDS……Page 302
Drugs for Treating Endoparasitic and Ectoparasitic Infestations……Page 304
Antimalarials……Page 306
Other Tropical Diseases……Page 308
Chemotherapy of Malignant Tumors……Page 310
Mechanisms of Resistance to Cytostatics (B)……Page 314
Inhibition of Immune Responses……Page 316
Antidotes and Treatment of Poisonings……Page 320
Therapy of Selected Diseases……Page 325
Hypertension……Page 326
Angina Pectoris……Page 328
Antianginal Drugs……Page 330
Acute Coronary Syndrome— Myocardial Infarction……Page 332
Congestive Heart Failure……Page 334
Hypotension……Page 336
Gout……Page 338
Obesity—Sequelae and Therapeutic Approaches……Page 340
Osteoporosis……Page 342
Rheumatoid Arthritis……Page 344
Migraine……Page 346
Common Cold……Page 348
Atopy and Antiallergic Therapy……Page 350
Bronchial Asthma……Page 352
Emesis……Page 354
Alcohol Abuse……Page 356
Local Treatment of Glaucoma……Page 358
Further Reading……Page 361
Picture Credits……Page 362
Drug Indexes……Page 363
A……Page 394
B……Page 396
C……Page 397
D……Page 399
E……Page 401
G……Page 402
H……Page 403
J,K……Page 404
M……Page 405
O……Page 407
P……Page 408
S……Page 410
T……Page 412
W,X……Page 413
Z……Page 414